The British Soap Awards' top honor went to EastEnders, while Coronation Street was the recipient of the most trophies.
Saturday night in Salford, Jane McDonald presided over the awards ceremony.
After Phillip Schofield left ITV last week, she took over as this morning's presenter.
Billy Mitchell's actor Perry Fenwick said, "From the bottom of our hearts, honestly, we are thrilled to bits, accepting the award for best British soap alongside the EastEnders cast. ".
Danielle Harold's portrayal of Lola Pearce-Brown, a character who recently passed away due to a brain tumor, helped the drama win the top leading performer award.
"Their time has been so precious to them and even more so to me, and I can't thank all of you enough for helping me," Harold said after dedicating the award to everyone who had been directly impacted by brain tumors. ".
At the ceremony held at Salford Quays' Lowry Theatre, the soap opera also took home awards for best young performer and villain of the year.
Six awards were given to Coronation Street, including best single episode and scene of the year for its depiction of an acid attack.
In the past year, Manchester has seen 330 acid attacks, according to Ryan Prescott, whose character Ryan Connor was hurt in the attack.
It was incredible, he said, to be a part of something that could shed light on a subject so delicate and one that affects far more people than we realize.
The head of casting for the television program Hollyoaks received the Tony Warren Award, formerly known as the outstanding achievement award (off screen), for winning best storyline. The Coronation Street creator, who passed away in 2016, is honored by the award.
Mark Charnock, who plays Marlon Dingle in Emmerdale, received the outstanding achievement award, and Doctors actors Chris Walker and Jan Pearson won the best on-screen partnership prize.
Presenting the awards, according to singer and travel presenter McDonald, is her ideal job because she is a "massive fan of the soap operas.".
She's also well-known for participating on the Loose Women panel and presenting the Bafta-winning Cruising With Jane McDonald series on Channel 5.
McDonald announced as the awards ceremony came to a close, "I'm off for a knees-up with all my favorite soap stars, I'm so excited. ".
Following his admission of lying about having an affair with a younger male colleague, Schofield quit ITV last week.
The former This Morning host claimed he had "lost everything" and did not see a future for his career in an interview with the BBC.